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Lisinopril: Uses, Side Effects, Interaction and Precautions

Lisinopril Medication and Drugs

Generic Name— Lisinopril
Brand Names— Prinivil, Qbrelis, Zestril

What Is Lisinopril?

Lisinopril is an ACE (angiotensin converting enzyme) inhibitor used to treat high blood pressures (hypertension). Lowering high blood pressure helps to prevent many diseases such as strokes, heart attack and kidney problems. Lisinopril works by relaxing blood vessels so blood can flow more easily. It can be taken by mouth with or without food or as directed by your physician, usually once daily.

The medication can be used by adults and children who are at least 6 years old.

Important Information:

It is advisable not to take this medicine if you have ever had angioedema. Also avoid the use of Lisinopril within 36 hours before or after taking medicine that contains sacubitril.

It is not recommended to take Lisinopril if you are pregnant because it could harm unborn baby. Stop taking this medication and ask your doctor right away.

If you are diabetic, don’t use Lisinopril together with any medication that contains aliskiren such as Tekturna, Tekamlo or Amturnide. Also avoid taking Lisinopril with aliskiren if you have kidney disease.


Tell your doctor or health care provider about all your current medication and any you start or stop using, especially —

  • Lithium
  • Potassium supplement
  • Diuretic or water pill
  • Gold injections to cure arthritis
  • Insulin or oral diabetes medicine
  • Medicine to prevent organ transplant rejection — sirolimus, everolimus, temsirolimus or tacrolimus
  • Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) — Ibuprofen (Advil, Motrin), Aspirin, Celecoxib, Diclofenac, Naproxen (Aleve), Indomethacin, Meloxicam, and others

Precautions While Taking Lisinopril:

Tell your doctor or health care provider if you have an allergic reaction or a history of other allergy. The medication may have inactive ingredients, which can cause allergic reactions or other problems. Call your doctor for more details.

Before taking this medicine, tell your doctor about the medical history, especially of —

  • History of an allergic reaction which included swelling of the lips, face, tongue or throat
  • Blood filtering procedures (such as LDL apheresis, dialysis)
  • High level of potassium in the bloodstream

Avoid drinking alcohol and the use of cannabis. Do not drive, use machinery, or do anything that needs alertness.

This medication may increase the levels of potassium in the body. Before using any potassium supplement or salt substitutes that contain potassium, ask your doctor or health care provider.

Lisinopril medication is not recommended during pregnancy. It may harm an unborn baby.

It is not clear whether this medication passes into breast milk. Consult your doctor if you are breast—feeding.

What Are The Side Effects Of Lisinopril?

Call your doctor or health care provider if you have —

  • Fever
  • Sore throat
  • Nausea
  • Weakness
  • Tingly feeling
  • Chest pain
  • Irregular heartbeats
  • Loss of movement
  • Little or no urination
  • Dark urine
  • A light—headed feeling, like you might pass out
  • Swelling in your feet or ankles
  • Feeling tired
  • Short of breath
  • Upper stomach pain
  • Itching
  • Loss of appetite
  • Clay—colored stools
  • Jaundice (yellowing of the skin or eyes)

Common Lisinopril side effects may include —

  • Cough
  • Dizziness
  • Headache
  • Chest pain

What Happens If I Miss A Dose Of Lisinopril?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What Happens If I Overdose?

Seek emergency medical help or call the Poison Help line at 1—800—222—1222.

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