GENERIC NAME: Avalglucosidase Alfa
BRAND NAME (S): Nexviazyme
DRUG CLASS: Lysosomal Enzymes
WHAT IS NEXVIAZYME?
Nexviazyme (Avalglucosidase) is a medication used to treat late-onset Pompe disease. It helps replace an enzyme that is missing in the people with a genetic disease called late-onset Pompe disease or GAA deficiency in the children at least 1 year old.
Nexviazyme belongs to a class of drugs, called Lysosomal Enzymes.
SIDE EFFECTS OF NEXVIAZYME:
Nexviazyme side-effects include:
- Skin redness
- Joint pain
- Muscle aches
- Shortness of breath
- Numbness and tingling.
Some serious side-effects may include:
- Hypersensitivity reactions including anaphylaxis
- Infusion-associated reactions (IARs).
HOW IS NEXVIAZYME GIVEN?
Nexviazyme is injected into your vein by your doctor or healthcare provider, usually once every 2 weeks.
Avalglucosidase medication should be given slowly over 4 to 5 hours.
It is also possible that your doctor may recommend you some other medicines to help prevent serious health side-effects or an allergic reaction.
Before taking Nexviazyme medication, tell your doctor or healthcare provider if you are allergic to it or if you have a history of any other allergy.
Tell your doctor or healthcare provider if you have ever had any disease; especially of:
- Heart disease
- Lung disease or breathing problems.
Tell your doctor if you are pregnant or planning to get pregnant. If Pompe disease has not been treated and you are having pregnancy then it may increase the risk of worsened breathing problems and muscle or joint problems.
It is not known whether this medicine is safe while breastfeeding. It may pass into breast milk. Tell your doctor if you are breastfeeding.
Tell your doctor or healthcare provider, if you are taking any other medications. Some medicines may interfere with Voclosporin. They may include:
- Certain medications
- Herbal products.
This is not a complete list. For more details, ask your doctor.